Neural Tube Defects

SYD: 21

Neural Tube Defects

Description: Spinal dysraphism, or neural tube defect (NTD), is a broad term encompassing a heterogeneous group of congenital spinal anomalies, which result from defective closure of the neural tube early in fetal life and anomalous development of the caudal cell mass. Neural tube defects are the second most common type of birth defect after congenital heart defects. The 2 most common NTDs are open spina bifida, also known as spina bifida cystica (SBC) or myelomeningocele, and anencephaly. Spina bifida occulta (SBO) is a bony defect of the spine covered by normal skin. It is mild form of spina bifida and is often asymptomatic. The term 'spinal dysraphia' refers to both SBC and SBO (Botto et al., 1999; Fineman et al., 1982).

There are no synonyms for this combination.

Category: (empty)

Developmental anomalies

Listed in the combination's profile :

There are no developmental anomalies for this combination.

Observed in MDB cases:

There are no developmental anomalies for this combination.
Case records
Associated malformative diseases
Associated genes
Associated signaling pathways
Close combinations