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Hydrocephalus, Non-communicating

DA: 774

Developmental anomaly information

Definition: Non-communicating hydrocephalus, or obstructive hydrocephalus, is caused by a CSF-flow obstruction (either due to external compression or intraventricular mass lesions). Foramen of Monro obstruction may lead to dilation of one or, if large enough (e.g., in colloid cyst), both lateral ventricles. The aqueduct of Sylvius, normally narrow to begin with, may be obstructed by a number of genetically or acquired lesions (e.g., atresia, ependymitis, hemorrhage, tumor) and lead to dilatation of both lateral ventricles as well as the third ventricle. Fourth ventricle obstruction will lead to dilatation of the aqueduct as well as the lateral and third ventricles. The foramina of Luschka and foramen of Magendie may be obstructed due to congenital failure of opening (e.g., Dandy-Walker malformation). The subarachnoid space surrounding the brainstem may also be obstructed due to inflammatory or hemorrhagic fibrosing meningitis, leading to widespread dilatation, including the fourth ventricle.


  • Obstructive hydrocephalus

Developmental anomaly parent: (empty)

Topology: Human body > Head and neck > Head > Cranium > Brain

System: Human body > Nervous system > Central nervous system

Developmental anomaly category: Malformation

Case records MDB257, MDB409, MDB276, MDB95, MDB352, MDB439, MDB444, MDB541
Observed in MDB cases
Observed in combinaisons (MDB)
Observed in malformative diseases (MDB)
Associated genes in profile
Associated genes in malformative diseases
Associated chromosomal diseases
Associated signaling pathways
Associated developmental anomalies

Here is the list of developmental anomalies associated with this developmental anomaly, based on the cases' information :

Last modified: 2008-12-15 21:14:14 by farideh

Created: 2008-10-20 21:48:53 by farideh

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