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Communicating hydrocephalus

DA: 666




Developmental anomaly information

Definition: Communicating hydrocephalus, also known as non-obstructive hydrocephalus, is caused by impaired cerebrospinal fluid resorption in the absence of any CSF-flow obstruction. It has been theorized that this is due to functional impairment of the arachnoid granulations, which are located along the superior sagittal sinus and is the site of cerebrospinal fluid resorption back into the venous system. Various neurologic conditions may result in communicating hydrocephalus, including subarachnoid/intraventricular hemorrhage, meningitis, Chiari malformation, and congenital absence of arachnoidal granulations (Pacchioni's granulations). Normal pressure hydrocephalus (NPH) is a particular form of communicating hydrocephalus, characterized by enlarged cerebral ventricles, with only intermittently elevated cerebrospinal fluid pressure. Hydrocephalus ex vacuo also refers to an enlargement of cerebral ventricles and subarachnoid spaces, and is usually due to brain atrophy (as it occurs in dementias), post-traumatic brain injuries and even in some psychiatric disorders, such as schizophrenia. As opposed to hydrocephalus, this is a compensatory enlargement of the CSF-spaces in response to brain parenchyma loss - it is not the result of increased CSF pressure.


Synonyms:

  • Low pressure hydrocephalus
  • Hydrocephalus ex-vacuo
  • non-obstructive hydrocephalus


Developmental anomaly parent: Hydrocephalus

Topology: Human body > Head and neck > Head > Cranium > Brain

System: Human body > Nervous system > Central nervous system > Brain

Developmental anomaly category: Malformation

Case records MDB17, MDB21, MDB43, MDB38, MDB220, MDB234, MDB267, MDB366, MDB443, MDB269, MDB2, MDB6, MDB248, MDB256, MDB313, MDB383, MDB447
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Observed in MDB cases
Observed in combinaisons (MDB)
Observed in malformative diseases (MDB)
  • () in case MDB
Associated genes in profile
Associated genes in malformative diseases
Associated chromosomal diseases
Associated signaling pathways
Associated developmental anomalies

Here is the list of developmental anomalies associated with this developmental anomaly, based on the cases' information :



Last modified: 2009-01-05 14:54:46 by farideh

Created: 2008-09-04 13:42:56 by farideh



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