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Spina bifida

DA: 64

Developmental anomaly information

Definition: Spinal dysraphism, or neural tube defect (NTD), is a broad term encompassing a heterogeneous group of congenital spinal anomalies, which result from defective closure of the neural tube early in fetal life and anomalous development of the caudal cell mass. Neural tube defects are the second most common type of birth defect after congenital heart defects. The 2 most common NTDs are open spina bifida, also known as spina bifida cystica (SBC) or myelomeningocele, and anencephaly. Spina bifida occulta (SBO) is a bony defect of the spine covered by normal skin. It is mild form of spina bifida and is often asymptomatic. The term 'spinal dysraphia' refers to both SBC and SBO (Botto et al., 1999; Fineman et al., 1982).


  • Spinal dysraphism
  • NTD
  • Neural Tube Defects

Developmental anomaly parent: (empty)

Topology: Human body

System: Human body > Nervous system > Central nervous system

Developmental anomaly category: Dysraphism

Case records MDB58

Humpath: 4137

OMIM: 182940

Observed in MDB cases
Observed in combinaisons (MDB)
Observed in malformative diseases (MDB)
Associated genes in profile
Associated genes in malformative diseases
Associated chromosomal diseases
Associated signaling pathways
Associated developmental anomalies

Here is the list of developmental anomalies associated with this developmental anomaly, based on the cases' information :

Last modified: 2008-12-23 20:45:31 by farideh

Created: 2008-02-25 01:00:00 by phsaw

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