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Transverse palmar crease, bilateral

DA: 198

Developmental anomaly information

Definition: In humans, a single transverse palmar crease is a single crease that extends across the palm of the hand, formed by the fusion of the two palmar creases that people typically have. The presence of a single transverse palmar crease can be, but is not always, a symptom of certain medical conditions such as Fetal alcohol syndrome and genetic abnormalities including Down syndrome and Noonan syndrome. Males are twice as likely as females to have this condition.


  • simian crease
  • simian line

Developmental anomaly parent: (empty)

Topology: Human body > Limbs > Upper limbs > Hand

System: integument & skin

Developmental anomaly category: Malformation

Case records MDB5, MDB30, MDB32, MDB99, MDB121, MDB124, MDB125, MDB132, MDB134, MDB142, MDB199, MDB227, MDB362, MDB363, MDB368, MDB432, MDB440, MDB441, MDB443, MDB448, MDB481, MDB515, MDB535, MDB4, MDB146, MDB265
Observed in MDB cases
Observed in combinaisons (MDB)
Observed in malformative diseases (MDB)
Associated genes in profile
Associated genes in malformative diseases
Associated chromosomal diseases
Associated signaling pathways
Associated developmental anomalies

Here is the list of developmental anomalies associated with this developmental anomaly, based on the cases' information :

Last modified: 2008-12-16 17:47:30 by farideh

Created: 2008-05-13 02:00:00 by phsaw

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